Research into cortical oxygen distribution, microcirculation, and the biosensors that reveal how the brain breathes — and what happens when it can't.
Research focus
My work is centered on the neurophysiology of the brain — particularly the oxygen dynamics and microcirculation that underpin neurological conditions.
Using innovative fluorescent oxygen biosensors (GeNL) to study oxygen distribution and dynamics within the living brain.
Investigating how the brain's energy metabolism is shaped by oxygen availability, linking cortical oxygen supply to metabolic demand in health and disease.
Developing and applying new genetically encoded biosensors for in vivo imaging to understand brain physiology.
Studying how cerebral oxygen availability changes with aging and in Alzheimer's disease, and how hypoxia contributes to neurodegeneration.
Unraveling the novel meningeal layer's role in cerebrospinal fluid flow and immune cell trafficking.
Elaborating on the mechanisms of molecular exchange across the blood-CSF barrier using bioluminescence imaging.
Latest
My master's student Stefanie Gregoriades has successfully defended the thesis — a well-deserved result and an excellent milestone. Congratulations, Stefanie!
LabMy master's student Mads U. E. Hansen has successfully defended his thesis — a well-deserved result and an excellent milestone. Congratulations, Mads!
LabPresented our work on hypoxic pockets and brain hypoxia in the symposium “Astroglial and Vascular Mechanisms of Metabolic Adaptations to Hypoxia”, and received a FENS Childcare Support Grant.
ConferenceSpeaker in symposium S53 “Astroglial and Vascular Mechanisms of Metabolic Adaptations to Hypoxia”, presenting real-time oxygen imaging of cortical hypoxic pockets in the healthy brain.
ConferenceInvited seminar at the Graduate School of Life Sciences, Tohoku University on oxygen imaging of hypoxic pockets in the mouse cerebral cortex.
Conference