Author: Felix
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2024 Lund Glymphatic Symposium
Conferences Talk and Poster In June I have been visiting the Lund Glymphatic Symposium and been selected to give a short talk about my latest publication “Oxygen Imaging of Hypoxic Pockets in the Mouse Cerebral Cortex”. My poster presentation got awarded with the 2nd price for the best poster. Thanks a lot to the organizers…
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Feature in PNAS about our recent Science paper
PNAS has featured our recent work from Science Magazine in their Journal Club section. This article discusses our groundbreaking study on oxygen dynamics in the brain, unveiling hypoxic pockets using a cutting-edge bioluminescence-based oxygen sensor. Additionally, it delves into the intriguing backstory behind our discovery of this innovative sensor. Check it out to explore more…
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New Science Paper: Oxygen imaging of hypoxic pockets in the mouse cerebral cortex
The human brain consumes vast amounts of energy, which is almost exclusively generated from a form of metabolism that requires oxygen. Consequently, the efficient and timely allocation and delivery of oxygen is critical to healthy brain function, however, the precise mechanics of this process have largely remained hidden from scientists. A new bioluminescence imaging technique,…
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Protocol to study molecule exchange between veneous blood and CSF
In bioluminescence imaging (BLI), the biochemical reaction between a substrate and enzyme triggers light emission upon convergence. Unlike fluorescence imaging, BLI does not require excitation. In this protocol, we utilize the high signal-to-background ratio of the reaction between luciferase and its substrate to study the exchange of molecules between blood and cerebrospinal fluid. We outline…