Category: Allgemein

  • Feature in PNAS about our recent Science paper

    Feature in PNAS about our recent Science paper

    PNAS has featured our recent work from Science Magazine in their Journal Club section. This article discusses our groundbreaking study on oxygen dynamics in the brain, unveiling hypoxic pockets using a cutting-edge bioluminescence-based oxygen sensor. Additionally, it delves into the intriguing backstory behind our discovery of this innovative sensor. Check it out to explore more…

  • New Science Paper: Oxygen imaging of hypoxic pockets in the mouse cerebral cortex

    New Science Paper: Oxygen imaging of hypoxic pockets in the mouse cerebral cortex

    The human brain consumes vast amounts of energy, which is almost exclusively generated from a form of metabolism that requires oxygen. Consequently, the efficient and timely allocation and delivery of oxygen is critical to healthy brain function, however, the precise mechanics of this process have largely remained hidden from scientists.    A new bioluminescence imaging technique,…

  • Protocol to study molecule exchange between veneous blood and CSF

    Protocol to study molecule exchange between veneous blood and CSF

    In bioluminescence imaging (BLI), the biochemical reaction between a substrate and enzyme triggers light emission upon convergence. Unlike fluorescence imaging, BLI does not require excitation. In this protocol, we utilize the high signal-to-background ratio of the reaction between luciferase and its substrate to study the exchange of molecules between blood and cerebrospinal fluid. We outline…

  • New Article in Science

    New Article in Science

    A mesothelium divides the subarachnoid space into functional compartments